Tag: C. diff

Weight Gain After Microbiota Transplant

Fecal microbiota transplantation (FMT) involves the transfer of fecal material from a healthy donor to the digestive tract of an ill recipient (most commonly, someone with refractory, or difficult to manage, C. difficile diarrhea). Transplanting the gut microbiota from a healthy individual to someone with C. diff has resulted in an impressive 90+ percent cure rate of the disease. Brenda…

Proton Pump Inhibitors Decrease Gut Microbial Diversity

Proton pump inhibitors (PPIs) are one of the most commonly prescribed medications in the United States, earning billions of dollars for pharmaceutical companies. PPIs markedly decrease the production of stomach acid as a treatment for conditions in the upper digestive tract such as acid reflux, ulcers, and Helicobacter pylori infection. While these medications are sometimes necessary in the short term,…

Give a Poop this Holiday Season with OpenBiome

“Give a sh!t. Save a life.” Literally. If you have yet to make end of the year charitable contributions, I have just the organization for you. OpenBiome’s slogan, although crude, couldn’t be more true. In an effort to raise funds the nonprofit organization is educating the public about the use of fecal transplants for treatment of refractory (resistant to treatment)…

RePOOPulating the Gut

The story unfolding about Clostridium difficile (C. diff for short) infection is one I pay close attention to. There is no effective treatment for recurrent C. diff infection, which puts this population at higher risk of complications, including death. In fact, it was recently announced that C. diff infection is now the ninth leading cause of gastrointestinal death, showing a…

Gut Balance is Key to Avoidance of C. difficile Infection

The bacterium Clostridium difficile (also known as C. diff) is a major pathogenic contributor to the development of antibiotic-associated diarrhea, or diarrhea that results from taking an antibiotic. According to the Centers for Disease Control (CDC), C. difficile diarrhea is linked to 14,000 deaths in the United States each year.1 Interestingly, first line treatment for C. diff infection is antibiotics—the…

Acid-suppressing Medications and Bacterial Infections

Last week the FDA issued a warning about the use of acid-suppressing medications known as proton pump inhibitors (PPIs) and the risk of Clostridium difficile-associated diarrhea (CDAD), a potentially life-threatening bacterial infection.1 The FDA states that in patients who develop diarrhea that does not improve, a diagnosis of CDAD should be considered. Clostridum difficile (C. diff) is a bacterium that…

Super Bugs and Genetically Modified Food

  I have blogged before on superbugs in our bodies—like C. diff, MRSA and Klebsiella pneumoniae. Superbugs is the term for bacteria that have developed antibiotic resistance, making the infections they cause very difficult to treat. The main reason for the development of these superbugs is the overuse of antibiotics—in medicine, food production (livestock) and even in hand soaps. Now,…

Antibiotics, Probiotics or Both for C. diff?

On May 27, 2011 a New York Times article reports that Sherwood Gorbach, a 71 year doctor, has been instrumental in the development of a new antibiotic, Dificid, also known as fidaxomicin, for treating C. difficle (C. diff) diarrhea. Dr. Gorbach spent most of his professional life as professor of medicine and public health at Tufts University. He is also…

Taking Antibiotics for a Bad Cold? Not so Good.

Over-prescription of antibiotics contributes to antibiotic resistance and affects the ability of bacteria to survive antibiotic treatment.  That’s very important because if antibiotics do not work for infections, there isn’t much else that will.  Now that’s scary! A recent study of patients hospitalized for respiratory infections found that in those who were diagnosed with a viral infection (antibiotics will not…

Another Testament of the Benefits of Probiotics

I love it when I hear from people who have taken my advice and to learn how they have personally benefitted from it. Just look at this incredible testimonial from a woman who decided to take her health into her own hands: “I am writing to let you know that the Ultimate Flora probiotics you recommend not only helped me…